The article examines secular and theological conceptions of human dignity in their relationship to biojurisprudence. Using comparative legal, hermeneutic, and formal dogmatic methods, it demonstrates that these conceptions generate a structural conflict of normativity, arising from divergences in the criteria of personhood and the moment at which full moral status emerges, in the understanding of the link between dignity and capacities, and in the interpretation of the relationship between person and nature. It is emphasized that the Russian constitutional legal order enshrines norms that preclude any hierarchization of human dignity, and the article substantiates the significance of theological traditions, as well as the mechanism of anthropological bioconstitutionalism (the categories of bioethical well being, vulnerability, and constitutional bioidentity) and the principle of minimal consensus, for shaping a sustainable model of constitutional legal protection of dignity under contemporary biotechnological challenges.