Published Date: 29.04.2026

Bioethical Aspects of Personal Dignity in the Modification of the Embryo Genome: Experience of the USA and Europe

Annotation

Changing the human genome already makes it possible to stop many hereditary diseases, but already there are many questions of both a legal and ethical nature related to the limits of what is allowed when changing the human genome. With the advent of technologies for editing the human genome, CRISPR-Cas9, TALENs, and ZFNs, issues of compliance with the bioethical rights of persons who have undergone genome modification have entered a new stage of discussion about the limits of what is allowed when changing the human genome and embryo. The article is devoted to the analysis of the legal regulation of interference in the embryo genome in the USA and European countries, as well as the identification of mechanisms for protecting the bioethical dignity of the embryo. In the current reality, the lack of global legal and ethical standards can lead to the creation of “designer” children, as well as increase social inequality in the world. Humanity should take a closer look at the issues of legal insecurity of the embryo, related to the implementation of the constitutional principle of personal dignity when interfering with the embryo's genome and editing it.




Library

1. Кравец И. Конституционная биоюриспруденция и достижение биоэтического благополучия (часть 1) / И. Кравец // Сравнительное конституционное обозрение. 2022. № 2 (147). C. 16–42.
2. Кузменкин И.В. Реализация конституционного принципа достоинства личности при клонировании человека / И.В. Кузменкин // Государственная власть и местное самоуправление. 2025. № 11. С. 50–53.
3. Мустафина-Бредихина Д.М. Редактирование генома эмбрионов и новорожденных: современное состояние проблемы / Д.М. Мустафина-Бредихина // Социальные новации и социальные науки. 2022. № 4. С. 29–39.
4. Романовский Г.Б. Правовое регулирование генетических исследований в России и за рубежом / Г.Б. Романовский // Сравнительное право. 2016. № 7. С. 93–101.
5. Beyond Therapy: Biotechnology and the Pursuit of Happiness / foreword by Leon R. Kass. Washington, D.C. : The President's Council on Bioethics, 2003. 328 p.
6. Kant I. Groundwork of the Metaphysics of Morals / I. Kant ; ed. by M.J. Gregor. Cambridge, UK : Cambridge University Press, 1998. 76 p.
7. Zibert, A. Tech billionaires back startup probing gene-edited ‘designer babies’ despite US ban: report / A. Zibert // The New York Post. 2025. 8 November.

Other articles